Vitamin App ReferenceSource-linked nutrient and bioactive reference
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For informational purposes only. Always consult a qualified medical professional before taking any supplement, herb, vitamin, mineral, or bioactive, especially if you use medications or have a medical condition. Read the full disclaimer.
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Sedatives / Driving

Items with sedation, sleep, alcohol, driving, or central nervous system caution context.

Sedating supplements can add to alcohol, sleep medications, anxiety medications, anesthesia, or impaired driving risk.

Anxiety

Anxiety references connect nutrients, botanicals, sleep context, and complementary-health topics that may affect anxious feelings or anxiety-related self-care discussions. This page is not an anxiety-disorder treatment guide.

Concern Tag

Chamomile has preliminary anxiety research and traditional relaxation use, but evidence is not conclusive and allergy, pregnancy, sedative, and anticoagulant contexts matter. | Passionflower has limited anxiety research and traditional relaxation use; sedation and pregnancy cautions should be reviewed before concentrated products. | Valerian is used for sleep and relaxation, but NCCIH says evidence is insufficient for anxiety and sedation cautions matter. | Caffeine can worsen anxiety, panic, sleep disruption, or heart-racing symptoms in sensitive people or at higher intakes. | Ashwagandha has stress/anxiety study context, but thyroid, pregnancy, autoimmune, liver, sedative, and medication cautions are important.

10 linked items - Persistent anxiety, panic attacks, trauma symptoms, severe insomnia, substance use, medication changes, pregnancy, or thoughts of self-harm need qualified care. Seek urgent or emergency help for thoughts of self-harm, feeling unsafe, severe panic with chest pain or fainting, psychosis, mania, or major behavior changes. Supplements can interact with medicines and should not replace therapy, medication, or urgent mental-health support.

Ashwagandha

Adaptogenic herb studied for stress, sleep, and perceived well-being outcomes.

Foods & BioactivesHigh caution

pregnancy/breastfeeding | thyroid disease | autoimmune disease | liver disease | sedatives

Herbs & Botanicals - Evidence: promising

Bacopa

Botanical studied for memory and attention outcomes over repeated use.

Foods & Bioactives

sedatives | pregnancy/breastfeeding

Additional Bioactives - Evidence: promising

Chamomile

Flower tea used traditionally for sleep, relaxation, and digestive comfort.

Foods & Bioactives

ragweed allergy | sedatives | blood thinners | pregnancy/breastfeeding

Herbs & Botanicals - Evidence: traditional use

Gotu Kola

Leaf used in Ayurveda and other traditions for skin, circulation, and cognitive contexts.

Foods & Bioactives

liver disease | sedatives | pregnancy/breastfeeding

Herbs & Botanicals - Evidence: emerging

Inositol

Sugar alcohol involved in cell-signaling pathways; myo-inositol and D-chiro-inositol are studied in PCOS and insulin-signaling contexts.

Foods & Bioactives

pregnancy/breastfeeding | fertility treatment | diabetes medications | GI effects

Additional Bioactives - Evidence: promising

Kava

Root beverage and extract traditionally used in Pacific Island cultures and studied for short-term anxiety symptom contexts.

Foods & BioactivesHigh caution

liver disease | alcohol | sedatives | driving | pregnancy/breastfeeding

Herbs & Botanicals - Evidence: promising

L-Theanine

Tea amino acid associated with relaxed alertness and modulation of excitatory neurotransmitter signaling.

Foods & Bioactives

Amino Acids - Evidence: promising

Lavender

Aromatic flower used as tea, essential oil, or standardized oral oil in relaxation and anxiety research contexts.

Foods & Bioactives

sedatives | pregnancy/breastfeeding | allergy | children

Herbs & Botanicals - Evidence: promising

Lemon Balm

Aromatic mint-family herb used traditionally for calm, sleep, and digestive comfort.

Foods & Bioactives

sedatives | thyroid medications

Herbs & Botanicals - Evidence: emerging

Mood & Stress

Mood and stress references connect nutrients involved in nervous-system function with botanicals studied for stress, sleep, anxiety, or perceived well-being outcomes.

Concern Tag

Saffron is studied for mood-related outcomes, but product, dose, pregnancy, and medication context need deeper review before strong app claims.

7 linked items - Depression, anxiety, panic, suicidality, trauma symptoms, mania, or major behavior changes need qualified care. Botanicals can interact with sedatives, antidepressants, thyroid disease, pregnancy, liver disease, and other conditions.

Passionflower

Aerial parts used traditionally for relaxation and sleep contexts.

Foods & Bioactives

sedatives | pregnancy/breastfeeding

Herbs & Botanicals - Evidence: emerging

Restless Legs

Restless legs references connect iron status, sleep disruption, caffeine/alcohol/nicotine context, pregnancy, kidney disease, neuropathy, and medications that can aggravate symptoms.

Concern Tag

Magnesium is often discussed for leg discomfort or sleep, but restless-legs evidence is not the same as official magnesium intake guidance. | Caffeine may aggravate restless legs or sleep disruption in some people, especially later in the day. | B12 belongs in neurologic symptom review contexts, but restless legs should not be assumed to be a B12 issue without evaluation. | Folate supports red blood cell formation and neurologic context, but RLS symptoms require cause-based assessment rather than broad supplementation.

5 linked items - Restless legs symptoms should be evaluated for iron deficiency, kidney disease, neuropathy, sleep apnea, pregnancy, and medication triggers. Iron supplements should only be used after iron studies and clinician guidance.

Restless Legs Syndrome

Restless legs syndrome symptoms, Iron deficiency and RLS, Caffeine alcohol nicotine RLS context, Pregnancy and RLS context, Medication aggravation context

SourceAcademic Review

National Institute of Neurological Disorders and Stroke - Acquired 2026-08-03 - Academic Review

Sleep

Sleep-related references connect nutrients and botanicals involved in relaxation, stimulant cautions, and sleep/stress study contexts.

Concern Tag

Valerian is used for sleep and relaxation, but can cause sedation and should be reviewed around alcohol, sedatives, driving, pregnancy, and surgery. | Chamomile tea is commonly used for relaxation, but concentrated products need caution with allergy, sedatives, anticoagulants, and pregnancy contexts. | Caffeine can disrupt sleep depending on dose, timing, sensitivity, and total daily intake. | Melatonin can help selected circadian-timing problems such as jet lag or delayed sleep-wake phase disorder, but it is not a general chronic-insomnia cure.

7 linked items - Sleep problems can reflect sleep apnea, stress, medication timing, caffeine, alcohol, pain, mood disorders, or medical conditions. Sedating supplements can interact with alcohol, driving, surgery, and medications.

Sleep Apnea

Sleep apnea references connect snoring, gasping, daytime sleepiness, weight and alcohol/caffeine context, and why supplements are not substitutes for sleep-study-based care.

Concern Tag

Caffeine can mask daytime sleepiness and disrupt sleep timing, but it does not treat breathing pauses during sleep. | Melatonin may help selected circadian-timing problems, but it does not treat airway obstruction or breathing pauses in sleep apnea. | Sedating supplements can worsen alertness risk or combine with alcohol and sleep medicines; sleep apnea symptoms should be evaluated instead of sedated over. | Ashwagandha is studied for sleep/stress measures but should not be used as a substitute for sleep apnea diagnosis or treatment.

5 linked items - Sleep apnea can increase cardiovascular and daytime-safety risk. Supplements, sedatives, alcohol, and sleep aids should not be used to mask symptoms or replace sleep testing and appropriate treatment.

Sleep Apnea Treatment

Sleep apnea treatment, CPAP PAP oral devices, Lifestyle changes, Alcohol caffeine smoking context

SourceAcademic Review

National Heart, Lung, and Blood Institute - Acquired 2026-08-03 - Academic Review

Thiamin (B1) symptoms

Deficiency: Fatigue or weakness, Irritability, Peripheral neuropathy. Too much: No established toxicity pattern from food or ordinary supplemental intake.

SymptomsDeficiency signsToo much / toxicity signs

No established toxicity pattern from food or ordinary supplemental intake

vitamin - Symptom reference

Valerian

Root used traditionally and studied for sleep and relaxation contexts.

Foods & Bioactives

sedatives | alcohol | driving | surgery | pregnancy/breastfeeding

Herbs & Botanicals - Evidence: emerging