Vitamin B6
Poultry and fish, Potatoes, Chickpeas, Bananas.
Back to TagsDepression, anxiety, panic, suicidality, trauma symptoms, mania, or major behavior changes need qualified care. Botanicals can interact with sedatives, antidepressants, thyroid disease, pregnancy, liver disease, and other conditions.
Source mix: Official Reference, Systematic Review, Traditional / Safety Reference, Food Database, Government Health Agency. Vitamin B6 Fact Sheet for Health Professionals Vitamin B12 Fact Sheet for Health Professionals Folate Fact Sheet for Health Professionals Magnesium Fact Sheet for Health Professionals Ashwagandha Supplementation for Anxiety and Stress: Systematic Review and Meta-Analysis Effect of Ashwagandha Extract on Sleep: A Systematic Review and Meta-Analysis Herbs at a Glance FoodData Central Mixing Medications and Dietary Supplements Can Endanger Your Health
Tag
Mood & Stress
Mood and stress references connect nutrients involved in nervous-system function with botanicals studied for stress, sleep, anxiety, or perceived well-being outcomes.
moodstressanxietycalmrelaxationmental wellbeingburnoutnervous system
Linked Items
7
May Support
6
Deficiency Signs
0
Cautions
1
Quick Compare
| Item | Type | Relationship | Evidence |
|---|---|---|---|
| Vitamin B6 | nutrient | May Support | Official NIH ODS nutrient-role framing; high-dose B6 can cause sensory neuropathy. Official Reference |
| Vitamin B12 | nutrient | May Support | Official NIH ODS nutrient-role framing. Official Reference |
| Folate | nutrient | May Support | Official NIH ODS nutrient-role framing. Official Reference |
| Magnesium | nutrient | May Support | Official NIH ODS nutrient-role framing; mood/sleep claims should remain evidence-specific. Official Reference |
| Ashwagandha | bioactive | May Support | Systematic-review evidence with botanical safety cautions. Systematic Review |
| L-Theanine | bioactive | May Support | Catalog item marked promising; claim-level mood/stress evidence can be expanded later. Food Database |
| Saffron | bioactive | Caution / Limited Evidence | Catalog review target; stronger claim-level sources should be added later. Traditional / Safety Reference |
Foods First
Vitamin B12
Meat and fish, Eggs and dairy foods, Fortified plant foods.
Folate
Leafy green vegetables, Legumes, Fortified grain products.
Magnesium
Nuts and seeds, Legumes, Whole grains, Leafy green vegetables.
Ashwagandha
Ashwagandha root.
L-Theanine
Green tea, black tea, white tea, matcha, some mushrooms.
Saffron
Saffron stigmas from Crocus sativus.
Medication & Safety Cautions
Vitamin B6
Vitamin B6 is involved in neurotransmitter synthesis and homocysteine metabolism. | Long-term excessive supplemental vitamin B6 can cause nerve damage.
Folate
Folate supports methylation and DNA synthesis; deficiency context can overlap with neurologic and mood evaluations. | The UL applies to folic acid from supplements and fortified foods, not naturally occurring food folate.
Magnesium
Magnesium supports normal nerve and muscle function. | The DRI UL applies to supplemental/pharmacological magnesium, not magnesium naturally present in food and water.
Ashwagandha
Ashwagandha extracts have systematic-review evidence for stress and anxiety measures, but product type and safety context matter. | pregnancy/breastfeeding | thyroid disease | autoimmune disease
Saffron
Saffron is studied for mood-related outcomes, but product, dose, pregnancy, and medication context need deeper review before strong app claims. | pregnancy/breastfeeding | mood medications
Key Studies & Fixed References
These are the dated references used for this tag. Live research searches can change; these links explain the fixed wording shown on this page.
NIH Office of Dietary Supplements | Acquired 2026-07-24 | Official Reference
Vitamin B6 neurotransmitter synthesis, Homocysteine metabolism, High-dose sensory neuropathy caution.
NIH Office of Dietary Supplements | Acquired 2026-07-23 | Official Reference
Cobalamin forms, B12 supplement forms, B12 absorption context.
NIH Office of Dietary Supplements | Acquired 2026-07-23 | Official Reference
Food folate, Folic acid, 5-MTHF.
NIH Office of Dietary Supplements | Acquired 2026-07-23 | Official Reference
Magnesium supplement forms, Magnesium bioavailability, Magnesium medication interactions.
Phytotherapy Research / PubMed | Acquired 2026-07-23 | Systematic Review
Ashwagandha stress evidence, Ashwagandha anxiety evidence.
PLOS One / PubMed | Acquired 2026-07-23 | Systematic Review
Ashwagandha sleep evidence, Ashwagandha safety-data limitations.
National Center for Complementary and Integrative Health | Acquired 2026-07-23 | Traditional / Safety Reference
Botanical safety framing, Herb evidence summaries.
U.S. Department of Agriculture | Acquired 2026-07-23 | Food Database
Food composition and natural source verification.
U.S. Food and Drug Administration | Acquired 2026-07-23 | Government Health Agency
Supplement-medication interaction warning language.
May Support
Vitamin B6
nutrientOfficial Reference
Vitamin B6 is involved in neurotransmitter synthesis and homocysteine metabolism.
Evidence note: Official NIH ODS nutrient-role framing; high-dose B6 can cause sensory neuropathy.
Sources: Vitamin B6 Fact Sheet for Health Professionals (2026-07-24)Official Reference
Vitamin B12
nutrientOfficial Reference
Vitamin B12 supports neurologic function and red blood cell formation.
Evidence note: Official NIH ODS nutrient-role framing.
Sources: Vitamin B12 Fact Sheet for Health Professionals (2026-07-23)Official Reference
Folate
nutrientOfficial Reference
Folate supports methylation and DNA synthesis; deficiency context can overlap with neurologic and mood evaluations.
Evidence note: Official NIH ODS nutrient-role framing.
Sources: Folate Fact Sheet for Health Professionals (2026-07-23)Official Reference
Magnesium
nutrientOfficial Reference
Magnesium supports normal nerve and muscle function.
Evidence note: Official NIH ODS nutrient-role framing; mood/sleep claims should remain evidence-specific.
Sources: Magnesium Fact Sheet for Health Professionals (2026-07-23)Official Reference
Ashwagandha
bioactiveSystematic Review
Ashwagandha extracts have systematic-review evidence for stress and anxiety measures, but product type and safety context matter.
Evidence note: Systematic-review evidence with botanical safety cautions.
Sources: Ashwagandha Supplementation for Anxiety and Stress: Systematic Review and Meta-Analysis (2026-07-23)Systematic Review, Effect of Ashwagandha Extract on Sleep: A Systematic Review and Meta-Analysis (2026-07-23)Systematic Review, Herbs at a Glance (2026-07-23)Traditional / Safety Reference
L-Theanine
bioactiveFood Database
L-theanine is associated with relaxed alertness and is naturally found in tea.
Evidence note: Catalog item marked promising; claim-level mood/stress evidence can be expanded later.
Sources: FoodData Central (2026-07-23)Food Database, Mixing Medications and Dietary Supplements Can Endanger Your Health (2026-07-23)Government Health Agency
Caution / Limited Evidence
Saffron
bioactiveTraditional / Safety Reference
Saffron is studied for mood-related outcomes, but product, dose, pregnancy, and medication context need deeper review before strong app claims.
Evidence note: Catalog review target; stronger claim-level sources should be added later.
Sources: Herbs at a Glance (2026-07-23)Traditional / Safety Reference, Mixing Medications and Dietary Supplements Can Endanger Your Health (2026-07-23)Government Health Agency