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Skin

Skin-related references connect nutrients and bioactives that support normal connective tissue, epithelial tissue, wound healing, barrier function, or that may be linked with skin changes when intake is inadequate or excessive.

skin healthrashflushingdry skinwound healingcollageneczemaacnehairnails
Skin symptoms can come from allergies, infection, medication reactions, autoimmune disease, hormones, nutrient deficiency, or high-dose supplement use. This page is a navigation aid, not a diagnosis or treatment plan.
Linked Items
11
May Support
6
Deficiency Signs
2
Cautions
3

Quick Compare

ItemTypeRelationshipEvidence
Vitamin CnutrientMay Support
Official nutrient-role framing from NIH ODS.
Official Reference
Vitamin AnutrientMay Support
Official NIH ODS fact sheet; UL applies to preformed vitamin A, not provitamin A carotenoids from foods.
Official Reference
ZincnutrientMay Support
Official NIH ODS fact sheet. Zinc is not a stand-alone treatment for skin conditions.
Official Reference
Vitamin EnutrientMay Support
Official NIH ODS fact sheet plus NCCIH caution about limited evidence for skin-condition supplements.
Official Reference
Biotin (B7)nutrientDeficiency Sign
Official NIH ODS deficiency framing. Routine high-dose biotin for hair, skin, and nails should not be implied from deficiency signs.
Official Reference
Riboflavin (B2)nutrientDeficiency Sign
Official NIH ODS deficiency framing.
Official Reference
Niacin (B3)nutrientPossible Side Effect
Official NIH ODS adverse-effect framing; the niacin UL is based on supplemental niacin and flushing.
Official Reference
Collagen PeptidesbioactiveMay Support
Systematic-review and meta-analysis evidence; not an official DRI nutrient.
Systematic Review
Hyaluronic AcidbioactiveMay Support
Randomized clinical trial evidence; product dose and study population matter.
Clinical Trial
Evening Primrose OilbioactiveCaution / Limited Evidence
NCCIH skin and evening primrose oil summaries.
Traditional / Safety Reference
Omega-3 Fish OilbioactiveCaution / Limited Evidence
NCCIH skin-condition evidence framing and NIH ODS omega-3 safety context.
Traditional / Safety Reference

Foods First

Vitamin C

Citrus fruit, Bell peppers, Berries, Broccoli.

Vitamin A

Liver and some organ meats, Eggs and dairy foods, Orange and dark-green vegetables through provitamin A carotenoids.

Zinc

Oysters and meat, Dairy foods, Legumes and seeds.

Vitamin E

Nuts and seeds, Vegetable oils, Wheat germ.

Niacin (B3)

Meat and poultry, Fish, Nuts, Enriched grains.

Collagen Peptides

Gelatin, bone broth, skin-on poultry, fish skin, slow-cooked connective tissue.

Hyaluronic Acid

Bone broth and connective tissue foods in small/variable amounts, organ meats, root vegetables and leafy greens support general skin nutrient intake but are not major direct sources.

Medication & Safety Cautions

Vitamin C

Required for collagen biosynthesis and wound-healing biology; also functions as an antioxidant. | Very high intakes can cause gastrointestinal symptoms and may be unsuitable for some people prone to kidney stones.

Vitamin A

Supports epithelial tissue and immune function; preformed vitamin A excess can cause dry or peeling skin and hair changes. | The UL applies to preformed vitamin A, not beta-carotene from foods. | High preformed vitamin A intake can be especially concerning during pregnancy.

Zinc

Involved in immune function, DNA and protein synthesis, and wound healing. | Long-term high-dose zinc can interfere with copper status.

Vitamin E

Functions as a fat-soluble antioxidant in cell membranes; skin-condition treatment claims should be kept separate from basic nutrient-role claims. | The DRI UL applies to synthetic vitamin E from supplements and fortified foods.

Biotin (B7)

Biotin deficiency is rare, but reported deficiency signs include thinning hair, brittle nails, and a scaly red rash around body openings. | High-dose biotin can interfere with some laboratory tests.

Niacin (B3)

Supplemental nicotinic acid can cause flushing, itching, tingling, rash, dizziness, and low blood pressure at higher intakes. | The UL applies to synthetic niacin from supplements and fortified foods.

Collagen Peptides

Hydrolyzed collagen has human-trial evidence for modest improvements in skin hydration and elasticity, but study design and product differences matter. | allergy | kidney disease

Evening Primrose Oil

Commonly promoted for atopic dermatitis and skin inflammation, but NCCIH says evidence is not sufficient and oral evening primrose oil has not been shown helpful for atopic dermatitis.

Omega-3 Fish Oil

Omega-3 fish oil is sometimes promoted for inflammatory skin conditions, but skin-condition treatment evidence is inconsistent and high-dose supplemental use needs bleeding-risk review. | blood thinners | bleeding risk | surgery

Source mix: Official Reference, Traditional / Safety Reference, Systematic Review, Clinical Trial.

Key Studies & Fixed References

These are the dated references used for this tag. Live research searches can change; these links explain the fixed wording shown on this page.

Zinc Fact Sheet for Health Professionals

NIH Office of Dietary Supplements | Acquired 2026-07-23 | Official Reference

Zinc supplement forms, Elemental zinc context, Zinc absorption and iron interaction.

Skin Conditions and Complementary Health Approaches

National Center for Complementary and Integrative Health | Acquired 2026-07-24 | Traditional / Safety Reference

Skin-condition supplement evidence caution, Atopic dermatitis supplement evidence, Complementary health skin framing.

Evening Primrose Oil: Usefulness and Safety

National Center for Complementary and Integrative Health | Acquired 2026-07-24 | Traditional / Safety Reference

Evening primrose oil, Atopic dermatitis evidence caution, Skin inflammation traditional use.

May Support

Deficiency Sign

Biotin (B7)

nutrientOfficial Reference

Biotin deficiency is rare, but reported deficiency signs include thinning hair, brittle nails, and a scaly red rash around body openings.

Evidence note: Official NIH ODS deficiency framing. Routine high-dose biotin for hair, skin, and nails should not be implied from deficiency signs.

Sources: Biotin Fact Sheet for Health Professionals (2026-07-24)Official Reference

Possible Side Effect

Niacin (B3)

nutrientOfficial Reference

Supplemental nicotinic acid can cause flushing, itching, tingling, rash, dizziness, and low blood pressure at higher intakes.

Evidence note: Official NIH ODS adverse-effect framing; the niacin UL is based on supplemental niacin and flushing.

Sources: Niacin Fact Sheet for Health Professionals (2026-07-24)Official Reference

Caution / Limited Evidence

Omega-3 Fish Oil

bioactiveTraditional / Safety Reference

Omega-3 fish oil is sometimes promoted for inflammatory skin conditions, but skin-condition treatment evidence is inconsistent and high-dose supplemental use needs bleeding-risk review.

Evidence note: NCCIH skin-condition evidence framing and NIH ODS omega-3 safety context.

Sources: Skin Conditions and Complementary Health Approaches (2026-07-24)Traditional / Safety Reference, Omega-3 Fatty Acids Fact Sheet for Health Professionals (2026-07-23)Official Reference